4.7 Article

A new compound with cytotoxic activities from the leaves of Panax ginseng CA Meyer

Journal

CHINESE CHEMICAL LETTERS
Volume 19, Issue 7, Pages 837-840

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2008.05.017

Keywords

Panax ginseng; 3,6,20(S)-Trihydroxy-12,23-epoxy-dammar-24-ene,6,20-Di-O-beta-D-glucopyranoside; Cytotoxic activity

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A new compound, 3,6,20(S)-trihydroxy-12,23-epoxydammar-24-ene,6,20-di-O-beta-D-glucopyranoside (1), was isolated from the leaves of Panax ginseng C. A. Meyer, whose structural elucidation was carried out by means of spectral analysis (including IR, HR-FAB-MS and NMR). This compound showed the moderate cytotoxic activities against U937 and HeLa cells by using the MTT method. (C) 2008 Li Jun Wu. Published by Elsevier B. V. on behalf of Chinese Chemical Society. All rights reserved.

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