Journal
CHINESE CHEMICAL LETTERS
Volume 19, Issue 8, Pages 947-950Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2008.05.032
Keywords
Monoamine oxidase; Fluorogenic probe; Assay
Categories
Funding
- Scientific Research Foundation for the Returned Overseas Chinese Scholars Fund
- Zhejiang Province [Z01105002]
- Returned Overseas Chinese Scholars Fund
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Monoamine oxidase is flavoenzymes, widely distributed in mammals. It is well recognized that MAOs serve an important role in metabolism that they have close relationship with health. Along with the discoveries between MAOs and neurotic disease, more and more studies have been jumped in. In this paper, we design a new probe for assaying the activities of MAOs. The results showed that the probe [7-(3-aminopropoxy)coumarin] is simple, effective and sensitive for MAOB. (C) 2008 Qing Zhu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
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