Journal
CHILDS NERVOUS SYSTEM
Volume 24, Issue 11, Pages 1345-1348Publisher
SPRINGER
DOI: 10.1007/s00381-008-0675-8
Keywords
growth hormone; Chiari malformation; syringomyelia; growth hormone deficiency; growth hormone therapy
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Introduction The association between hypopituitarism, Chiari I malformation, and syringomyelia has been recently recognized. Most of the reported patients suffered perinatal injury or asphyxia. Materials and methods We present the case of a premature child without identifiable perinatal injury, who was recognized to have growth hormone (GH) deficiency, Chiari I malformation, and syringohydromyelia. Conclusion There was a resolution of syrinx and tonsillar herniation after GH replacement.
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