Journal
CHEST
Volume 143, Issue 2, Pages 494-501Publisher
ELSEVIER SCIENCE BV
DOI: 10.1378/chest.12-0598
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T helper 17 (Th17) cytokines are now widely believed to be critical for the regulation of various chronic immune diseases. Investigations have revealed a significant role for IL-17 cytokines in regulating inflammation and modulating lung and airway structural cells in asthma and COPD. In this review, our current understanding of the role of Th17-associated cytokines in airway diseases is summarized. Therapeutic approaches targeting IL-17 during asthma and COPD are also discussed. CHEST 2013; 143(2):494-501
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