Journal
CHEMOTHERAPY
Volume 55, Issue 4, Pages 228-233Publisher
KARGER
DOI: 10.1159/000219436
Keywords
Chagas' disease; Amiodarone; Itraconazole
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In the Americas, approximately 20 million people suffer from the chronic phases of Chagas' disease, of which chagasic cardiomyopathy is the most important clinical feature. The elimination of Trypanosoma cruzi is a pivotal step in arresting the evolution of the disease. Unfortunately, currently available chemotherapy is mostly ineffective due to its limited efficacy and toxic side effects. The following case highlights the efficacy of new diagnostic and follow-up methods in the evaluation of novel trypanocidal compounds such as amiodarone and itraconazole. Copyright (C) 2009 S. Karger AG, Basel
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