Journal
CHEMOSPHERE
Volume 80, Issue 11, Pages 1268-1273Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.chemosphere.2010.06.055
Keywords
Adsorption; Ampicillin; Nanoparticles; Alumina; Pharmaceutical contamination; Fate and transport
Categories
Funding
- Hope College Department of Chemistry
- Hope College Department of Geological and Environmental Sciences
- John Soeters and Willard Wichers Development Fund
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Transport of antibiotics in soil-water systems is controlled in part by adsorption to nanometer-size (10(-9) m) particles. Batch adsorption experiments were performed with ampicillin, a common amphoteric antibiotic, and 50 nm-Al2O3 (alpha-alumina) at different pH conditions. Sorption to Al2O3 can be described by linear isotherms for 2.9 mu m-2.9 mM ampicillin concentrations. Distribution coefficients (K-d) are 11.1 (+/-0.32) L kg(-1) at pH 2, 0.55 (+/-.04) L kg(-1) at pH 4, 21.9 (+/-0.9) L kg(-1) at pH 6, and 39.5 (+/-2.2) L kg(-1) at pH 8. At pH 2, similar to 47% of the initially adsorbed drug was removable by rinsing, at pH 4-56% was removed. Only 7% of the drug could be removed by rinsing at pH 6, and 3% at pH 8. Weak electrostatic forces dominate at pH < 4, and stronger attachment mechanisms at higher pH. Low yields in rinsing (desorption) experiments at pH >= 6 indicate strong attachment mechanisms, either electrostatic or possibly surface complexation. (C) 2010 Elsevier Ltd. All rights reserved.
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