4.5 Review

Small-Molecule Regulators of Autophagy and Their Potential Therapeutic Applications

Related references

Note: Only part of the references are listed.
Article Dentistry, Oral Surgery & Medicine

Curcumin-induced autophagy contributes to the decreased survival of oral cancer cells

Ji Young Kim et al.

ARCHIVES OF ORAL BIOLOGY (2012)

Review Chemistry, Multidisciplinary

Autophagy-regulating small molecules and their therapeutic applications

Kyung-Hwa Baek et al.

CHEMICAL SOCIETY REVIEWS (2012)

Article Neurosciences

Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity

Jae-Kyo Jeong et al.

NEUROSCIENCE RESEARCH (2012)

Article Chemistry, Medicinal

Curcumin Induces Autophagy in ACC-MESO-1 Cells

Yoshikane Yamauchi et al.

PHYTOTHERAPY RESEARCH (2012)

Review Oncology

Deconvoluting the context-dependent role for autophagy in cancer

Eileen White

NATURE REVIEWS CANCER (2012)

Article Biochemistry & Molecular Biology

Sensitizing effect of 3-methyladenine on radiation-induced cytotoxicity in radio-resistant HepG2 cells in vitro and in tumor xenografts

Hsien-Chun Tseng et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2011)

Review Biochemistry & Molecular Biology

Discovery of Small Molecules that Target Autophagy for Cancer Treatment

L. Wu et al.

CURRENT MEDICINAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Lucanthone Is a Novel Inhibitor of Autophagy That Induces Cathepsin D-mediated Apoptosis

Jennifer S. Carew et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Cell Biology

Preclinical Testing of the Akt Inhibitor Triciribine in T-Cell Acute Lymphoblastic Leukemia

Camilla Evangelisti et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2011)

Review Biochemistry & Molecular Biology

Chemical modulators of autophagy as biological probes and potential therapeutics

Angeleen Fleming et al.

NATURE CHEMICAL BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Resveratrol-Activated AMPK/SIRT1/Autophagy in Cellular Models of Parkinson's Disease

Yuncheng Wu et al.

NEUROSIGNALS (2011)

Article Endocrinology & Metabolism

Antiestrogenic Effects of the Novel Sphingosine Kinase-2 Inhibitor ABC294640

James W. Antoon et al.

ENDOCRINOLOGY (2010)

Article Oncology

Sorafenib induces apoptosis and autophagy in prostate cancer cells in vitro

Anders Ullen et al.

INTERNATIONAL JOURNAL OF ONCOLOGY (2010)

Review Oncology

Autophagy: cellular and molecular mechanisms

Danielle Glick et al.

JOURNAL OF PATHOLOGY (2010)

Article Pharmacology & Pharmacy

A Novel Sphingosine Kinase Inhibitor Induces Autophagy in Tumor Cells

Vladimir Beljanski et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)

Article Medicine, General & Internal

Cell Self-Eating (Autophagy) Mechanism in Alzheimer's Disease

Sarah F. Funderburk et al.

MOUNT SINAI JOURNAL OF MEDICINE (2010)

Review Immunology

Autophagy and Tumorigenesis

Srirupa Roy et al.

SEMINARS IN IMMUNOPATHOLOGY (2010)

Editorial Material Cell Biology

RAD001 (everolimus) induces autophagy in acute lymphoblastic leukemia

Roman Crazzolara et al.

AUTOPHAGY (2009)

Article Biochemistry & Molecular Biology

Autophagy Inhibition Enhances Apoptosis Induced by Ginsenoside Rk1 in Hepatocellular Carcinoma Cells

Hyeonseok Ko et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Autophagy Suppresses Tumorigenesis through Elimination of p62

Robin Mathew et al.

Review Biochemistry & Molecular Biology

The late stages of autophagy: how does the end begin?

T. Noda et al.

CELL DEATH AND DIFFERENTIATION (2009)

Article Biochemistry & Molecular Biology

The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1

J. M. Vicencio et al.

CELL DEATH AND DIFFERENTIATION (2009)

Review Pharmacology & Pharmacy

Chloroquine and its analogs: A new promise of an old drug for effective and safe cancer therapies

V. Raja Solomon et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2009)

Article Plant Sciences

Autophagic and apoptotic mechanisms of curcumin-induced death in K562 cells

Yan-Li Jia et al.

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2009)

Article Oncology

Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma

Vanessa Milano et al.

MOLECULAR CANCER THERAPEUTICS (2009)

Article Transplantation

Endoplasmic reticulum stress induces autophagy in renal proximal tubular cells

Takahisa Kawakami et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2009)

Review Physiology

Autophagy: molecular machinery, regulation, and implications for renal pathophysiology

Sudharsan Periyasamy-Thandavan et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2009)

Review Cell Biology

Autophagy -: An emerging target for cancer therapy

Maria Hoyer-Hansen et al.

AUTOPHAGY (2008)

Article Biochemistry & Molecular Biology

Inhibition of histone deacetylase1 induces autophagy

Meeyeon Oh et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)

Review Cardiac & Cardiovascular Systems

Crosstalk between autophagy and apoptosis in heart disease

Kazuhiko Nishida et al.

CIRCULATION RESEARCH (2008)

Article Cell Biology

Induction of autophagy during extracellular matrix detachment promotes cell survival

Christopher Fung et al.

MOLECULAR BIOLOGY OF THE CELL (2008)

Article Cell Biology

Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG

Eisuke Itakura et al.

MOLECULAR BIOLOGY OF THE CELL (2008)

Article Biochemistry & Molecular Biology

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

Andrea Williams et al.

NATURE CHEMICAL BIOLOGY (2008)

Article Multidisciplinary Sciences

Ceramide starves cells to death by downregulating nutrient transporter proteins

Garret G. Guenther et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Oncology

The roles of therapy-induced autophagy and necrosis in cancer treatment

Ravi K. Amaravadi et al.

CLINICAL CANCER RESEARCH (2007)

Review Oncology

Models, mechanisms and clinical evidence for cancer dormancy

Julio A. Aguirre-Ghiso

NATURE REVIEWS CANCER (2007)

Review Cell Biology

Autophagosome formation: Core machinery and adaptations

Zhiping Xie et al.

NATURE CELL BIOLOGY (2007)

Article Cell Biology

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

Yoshinori Takahashi et al.

NATURE CELL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Caspase-independent autophagic cytotoxicity in etoposide-treated CaSki cervical carcinoma cells

Seung-Baek Lee et al.

DNA AND CELL BIOLOGY (2007)

Article Cell Biology

Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis

Vassiliki Karantza-Wadsworth et al.

GENES & DEVELOPMENT (2007)

Article Biochemistry & Molecular Biology

DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells

M. Katayama et al.

CELL DEATH AND DIFFERENTIATION (2007)

Article Biochemistry & Molecular Biology

Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival

Wen-Xing Ding et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Cell Biology

Role of autophagy in cancer - Management of metabolic stress

Shengkan Jin et al.

AUTOPHAGY (2007)

Article Biochemistry & Molecular Biology

Autophagy delays apoptotic death in breast cancer cells following DNA damage

M. J. Abedin et al.

CELL DEATH AND DIFFERENTIATION (2007)

Article Biochemistry & Molecular Biology

Autophagy is activated for cell survival after endoplasmic reticulum stress

Maiko Ogata et al.

MOLECULAR AND CELLULAR BIOLOGY (2006)

Article Cell Biology

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis

Shida Yousefi et al.

NATURE CELL BIOLOGY (2006)

Article Cell Biology

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

Chengyu Liang et al.

NATURE CELL BIOLOGY (2006)

Article Cell Biology

Lithium induces autophagy by inhibiting inositol monophosphatase

S Sarkar et al.

JOURNAL OF CELL BIOLOGY (2005)

Article Cell Biology

Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy

Y Kabeya et al.

MOLECULAR BIOLOGY OF THE CELL (2005)

Article Biochemistry & Molecular Biology

Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1

F Scarlatti et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

T Kanzawa et al.

CELL DEATH AND DIFFERENTIATION (2004)

Article Oncology

Resveratrol-induced autophagocytosis in ovarian cancer cells

AW Opipari et al.

CANCER RESEARCH (2004)

Article Biochemistry & Molecular Biology

Autophagy: a regulated bulk degradation process inside cells

T Yoshimori

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)

Article Multidisciplinary Sciences

Apoptotic and autophagic cell death induced by histone deacetylase inhibitors

YF Shao et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Review Oncology

Mammalian target of rapamycin (mTOR) inhibitors as anti-cancer agents

RD Rao et al.

CURRENT CANCER DRUG TARGETS (2004)

Review Biochemistry & Molecular Biology

Regulation and role of autophagy in mammalian cells

AJ Meijer et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L

J Hemelaar et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Autophagy regulates the processing of amino terminal huntingtin fragments

ZH Qin et al.

HUMAN MOLECULAR GENETICS (2003)

Article Multidisciplinary Sciences

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

ZY Yue et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

B Ravikumar et al.

HUMAN MOLECULAR GENETICS (2002)

Article Multidisciplinary Sciences

A ubiquitin-like system mediates protein lipidation

Y Ichimura et al.

NATURE (2000)

Article Cell Biology

Tor-mediated induction of autophagy via an Apg1 protein kinase complex

Y Kamada et al.

JOURNAL OF CELL BIOLOGY (2000)