☆ 4.5 Article

Overcoming the Limitations of Fragment Merging: Rescuing a Strained Merged Fragment Series Targeting Mycobacterium tuberculosis CYP121

CHEMMEDCHEM (2013)

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Journal

CHEMMEDCHEM
Volume 8, Issue 9, Pages 1451-1456

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cmdc.201300219

Keywords

conformation analysis; cytochromes; drug discovery; fragment-based; tuberculosis

Categories

Chemistry, Medicinal Pharmacology & Pharmacy

Funding

  1. EC
  2. BBSRC [BB/I019227/1, BB/I019669/1]
  3. Sir Mark Oliphant Cambridge Australia Scholarship
  4. Cambridge Trusts
  5. BBSRC [BB/I019669/1, BB/I019227/1] Funding Source: UKRI
  6. Biotechnology and Biological Sciences Research Council [BB/I019227/1, BB/I019669/1] Funding Source: researchfish

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