☆ 4.5 Article

Dual Dehydrosqualene/Squalene Synthase Inhibitors: Leads for Innate Immune System-Based Therapeutics

CHEMMEDCHEM (2012)

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Journal

CHEMMEDCHEM
Volume 7, Issue 4, Pages 561-564

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cmdc.201100589

Keywords

immunology; isoprenoid biosynthesis; neutrophil extracellular traps; virulence factor; X-ray diffraction

Categories

Chemistry, Medicinal Pharmacology & Pharmacy

Funding

  1. US National Institutes of Health (NIH) [AI-074233]
  2. US Department of Energy [DE-AC02-06CH11357]
  3. Michigan Economic Development Corporation
  4. Michigan Technology Tri-Corridor [085P000817]

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