4.5 Article

Development of Isoxazoline-Containing Peptidomimetics as Dual αvβ3 and α5β1 Integrin Ligands

Related references

Note: Only part of the references are listed.
Review Oncology

Advances in Imaging Target Delineation

Klaudia U. Hunter et al.

CANCER JOURNAL (2011)

Article Nanoscience & Nanotechnology

Integrin alpha(v)beta(3)-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy

Huan Xie et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2011)

Article Cell Biology

Integrin α5β1 facilitates cancer cell invasion through enhanced contractile forces

Claudia Tanja Mierke et al.

JOURNAL OF CELL SCIENCE (2011)

Editorial Material Radiology, Nuclear Medicine & Medical Imaging

PET of αvβ3-Integrin and αvβ5-Integrin Expression with 18F-Fluciclatide for Assessment of Response to Targeted Therapy: Ready for Prime Time?

Ambros J. Beer et al.

JOURNAL OF NUCLEAR MEDICINE (2011)

Review Biochemistry & Molecular Biology

Towards novel paradigms for cancer therapy

V. Pavet et al.

ONCOGENE (2011)

Review Biochemistry & Molecular Biology

The tail of integrin activation

Nicholas J. Anthis et al.

TRENDS IN BIOCHEMICAL SCIENCES (2011)

Review Cell Biology

Integrins

Malgorzata Barczyk et al.

CELL AND TISSUE RESEARCH (2010)

Article Biochemistry & Molecular Biology

Inhibition of HIV-1 Replication by Isoxazolidine and Isoxazole Sulfonamides

Belinda Loh et al.

CHEMICAL BIOLOGY & DRUG DESIGN (2010)

Article Chemistry, Multidisciplinary

Total Syntheses of Tubulysins

Taku Shibue et al.

CHEMISTRY-A EUROPEAN JOURNAL (2010)

Review Biochemistry & Molecular Biology

Small Molecule Antagonists of Integrin Receptors

A. Perdih et al.

CURRENT MEDICINAL CHEMISTRY (2010)

Review Biochemistry & Molecular Biology

A New View of Carcinogenesis and an Alternative Approach to Cancer Therapy

Miguel Lopez-Lazaro

MOLECULAR MEDICINE (2010)

Review Chemistry, Multidisciplinary

Ligands for Mapping αvβ3-Integrin Expression in Vivo

Margret Schottelius et al.

ACCOUNTS OF CHEMICAL RESEARCH (2009)

Article Biochemistry & Molecular Biology

Mapping the ligand-binding pocket of integrin α5β1 using a gain-of-function approach

A. Paul Mould et al.

BIOCHEMICAL JOURNAL (2009)

Article Biochemistry & Molecular Biology

Expanding the repertoire of small molecule transcriptional activation domains

Ryan J. Casey et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2009)

Article Multidisciplinary Sciences

α5β1-Integrin controls ebolavirus entry by regulating endosomal cathepsins

Kathryn L. Schornberg et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biochemistry & Molecular Biology

Rational design of highly active and selective ligands for the α5β1 integrin receptor

Dominik Heckmann et al.

CHEMBIOCHEM (2008)

Review Biochemistry & Molecular Biology

ANTI-ADHESION evolves to a promising therapeutic concept in oncology

R. Schmidmaier et al.

CURRENT MEDICINAL CHEMISTRY (2008)

Article Chemistry, Organic

Synthesis of Ethyl 5-Hydroxyisoxazolidine-4-carboxylates via Michael Addition/Intramolecular Hemiketalisation

Fides Benfatti et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2008)

Review Immunology

Integrin-associated proteins as potential therapeutic targets

Joseph M. Cantor et al.

IMMUNOLOGICAL REVIEWS (2008)

Review Chemistry, Medicinal

Multi-target-directed ligands to combat neurodegenerative diseases

Andrea Cavalli et al.

JOURNAL OF MEDICINAL CHEMISTRY (2008)

Review Biotechnology & Applied Microbiology

Molecular imaging in drug development

Juergen K. Willmann et al.

NATURE REVIEWS DRUG DISCOVERY (2008)

Article Chemistry, Organic

Diastereoselective synthesis of D-xylo-isoxazolidinyl nucleosides

Eva Hyrosova et al.

TETRAHEDRON (2008)

Review Oncology

Integrins in angiogenesis and lymphangiogenesis

Christie J. Avraamides et al.

NATURE REVIEWS CANCER (2008)

Review Biochemistry & Molecular Biology

Cell adhesion molecules: Potential therapeutic & diagnostic implications

Shaker A. Mousa

MOLECULAR BIOTECHNOLOGY (2008)

Review Oncology

Anti-cancer therapies targeting the tumor stroma

Valeska Hofmeister et al.

CANCER IMMUNOLOGY IMMUNOTHERAPY (2008)

Article Biochemistry & Molecular Biology

Synthesis and biological evaluation of non-peptide αvβ3/α5β1 integrin dual antagonists containing 5,6-dihydropyridin-2-one scaffolds

Fides Benfatti et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2007)

Review Oncology

Alpha-v integrins as therapeutic targets in oncology

Jeffrey A. Nemeth et al.

CANCER INVESTIGATION (2007)

Article Chemistry, Multidisciplinary

Transcriptional up-regulation in cells mediated by a small molecule

Steven P. Rowe et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

Article Chemistry, Organic

Enantioselectively organocatalytic Michael addition of ketones to alkylidene malonates

Chun-Li Cao et al.

JOURNAL OF ORGANIC CHEMISTRY (2007)

Review Pharmacology & Pharmacy

Fragments, network biology and designing multiple ligands

Richard Morphy et al.

DRUG DISCOVERY TODAY (2007)

Article Chemistry, Organic

Nonpeptide integrin antagonists: RGD mimetics incorporating substituted azabicycloalkanes as amino acid replacements

Leonardo Manzoni et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2007)

Article Chemistry, Multidisciplinary

The constrained amino acid beta-Acc confers potency and selectivity to integrin ligands

Sylwia Urman et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)

Article Chemistry, Multidisciplinary

Probing integrin selectivity: Rational design of highly active and selective ligands for the alpha 5 beta 1 and alpha v beta 3 integrin receptor

Dominik Heckmann et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)

Article Chemistry, Medicinal

The scaffold tree - Visualization of the scaffold universe by hierarchical scaffold classification

Ansgar Schuffenhauer et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2007)

Article Biochemistry & Molecular Biology

New concepts regarding focal promotion of cell migration adhesion kinase and proliferation

Braden D. Cox et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2006)

Article Chemistry, Medicinal

Ligand binding analysis for human α5β1 integrin:: Strategies for designing new α5β1 integrin antagonists

L Marinelli et al.

JOURNAL OF MEDICINAL CHEMISTRY (2005)

Review Biochemistry & Molecular Biology

Dual antagonists of integrins

K Nadrah et al.

CURRENT MEDICINAL CHEMISTRY (2005)

Review Biochemistry & Molecular Biology

Non peptidic alpha(V)beta(3) antagonists: Recent developments

B Cacciari et al.

CURRENT MEDICINAL CHEMISTRY (2005)

Article Chemistry, Medicinal

Synthesis and biological evaluation of nonpeptide integrin antagonists containing spirocyclic scaffolds

JM Smallheer et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)

Article Chemistry, Multidisciplinary

A concise approach to structurally diverse β-amino acids

AR Minter et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)

Article Biochemistry & Molecular Biology

Latent production of angiotensin I-converting enzyme inhibitors from buckwheat protein

CH Li et al.

JOURNAL OF PEPTIDE SCIENCE (2002)

Article Multidisciplinary Sciences

Integrin activation controls metastasis in human breast cancer

B Felding-Habermann et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Chemistry, Multidisciplinary

Catalytic enantioselective alkylation of heteroaromatic compounds using alkylidene malonates

W Zhuang et al.

CHEMICAL COMMUNICATIONS (2001)

Article Biochemistry & Molecular Biology

Regulation of integrin αvβ3-mediated endothelial cell migration and angiogenesis by integrin α5β1 and protein kinase A

S Kim et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)