Journal
CHEMISTRY-AN ASIAN JOURNAL
Volume 6, Issue 5, Pages 1156-1162Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/asia.201000818
Keywords
green chemistry; nanoparticles; proteins; selenium; semiconductors
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Funding
- National 863 Hi-tech Project of China [2007AA022004]
- National Key Basic Research Program (973 Project) [2010CB933901, 2011CB933100]
- Important National Science & Technology Specific Projects [2009ZX10004-311]
- National Natural Scientific Fund [20803040]
- New Century Excellent Talent of Ministry of Education of China [NCET-08-0350]
- Shanghai Science and Technology Fund [10XD1406100]
- Shanghai Jiao Tong University
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Bovine serum albumin (BSA)-conjugated MxSey (M = Ag, Cd, Pb, Cu) nanomaterials with different shapes and sizes were synthesized in water at room temperature by a protein-directed, solution-phase, green synthetic method. The method features very low energy consumption and non-toxic reagents with high yields of concentrated nanoparticles. The obtained bioconjugated nanoparticles have good dispersibility, bioactivity, and biocompatibility. In addition, various functional groups of protein on the surface of the nanocrystals are suitable for further biological interactions or couplings, which is very important for further biological applications.
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