4.6 Article

Palladium/Norbornene-Mediated Tandem C-H Amination/C-I Alkenylation Reaction of Aryl Iodides with Secondary Cyclic O-Benzoyl Hydroxylamines and Activated Terminal Olefins

Journal

CHEMISTRY-A EUROPEAN JOURNAL
Volume 20, Issue 15, Pages 4237-4241

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201400084

Keywords

alkenylation; CH amination; norbornene; palladium; tandem reaction

Funding

  1. National Natural Science Foundation of China [21202065]
  2. Specialized Research Fund for the Doctoral Program of Higher Education [20123604120003]
  3. Sponsored Program for Cultivating Youths of Outstanding Ability from Jiangxi Normal University

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A novel palladium-catalyzed norbornene-mediated three-component reaction for the construction of ortho-alkenyl aromatic tertiary amines has been achieved, which represents a useful extension of the Catellani-type tandem ortho-selective CH amination transformations.

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