Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 20, Issue 35, Pages 11171-11175Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201402920
Keywords
DOSY spectroscopy; homonuclear broadband decoupling; mixture analysis; NMR spectroscopy; pure shift
Categories
Funding
- Austrian Science Foundation (FWF) [P24742]
- Austrian Academy of Sciences
- Austrian Science Fund (FWF) [P24742] Funding Source: Austrian Science Fund (FWF)
- Austrian Science Fund (FWF) [P 24742] Funding Source: researchfish
Ask authors/readers for more resources
For the analysis of compound mixtures by NMR spectroscopy, it is important to assign the different peaks to the individual constituents. Diffusion-ordered spectroscopy (DOSY) is often used for the separation of signals based on their self-diffusion coefficient. However, this method often fails in the case of signal overlap, which is a particular problem for H-1-detected DOSY spectra. Herein, an approach that allows the acquisition of homonuclear broadband-decoupled DOSY spectra without the introduction of an additional decoupling dimension, by instant decoupling during acquisition, is presented. It was demonstrated on a mixture of six alcohols, and the investigation of the binding of a dodecapeptide to membrane mimetics.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available