Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 20, Issue 38, Pages 12015-12019Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201403113
Keywords
1,2-migration; 1-naphthols; furans; gold; homogeneous catalysis
Categories
Funding
- National Natural Science Foundation of China [21125210, 21121062, 21372244, 21172248]
- Chinese Academy of Science
- Major State Basic Research Development Program [2011CB808700]
Ask authors/readers for more resources
Gold-catalyzed cascade cyclization/ 1,2-rearrangement of 1-(2-furanyl)phenyl propargyl alcohols has been developed, which provides a rapid and efficient access to multisubstituted 1-naphthols bearing an enal or enone moiety with high stereoselectivity. The (Z)- or (E)-stereochemistry can be easily controlled by choosing protected- or non-protected substrates. The utility of the methodology has been illustrated in the first total synthesis of wailupemycin G.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available