4.6 Article

Convenient Synthesis of Functionalized Bis-ureidopyrimidinones Based on Thiol-yne Reaction

Journal

CHEMISTRY-A EUROPEAN JOURNAL
Volume 20, Issue 37, Pages 11699-11702

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201402955

Keywords

bis-ureidopyrimidinones; hydrogen bonds; supramolecular chemistry; supramolecular polymers; thiol-yne reaction

Funding

  1. 973 Program [2013CB933800, 2013CB834505]
  2. National Natural Science Foundation of China [21222210, 91027041, 21272243]
  3. Chinese Academy of Sciences (100 Talents Program)

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The preparation of functionalized bis-ureidopyrimidinones (Bis-UPy) through the thiol-yne reaction is described. Various Bis-UPys with different functional groups were synthesized by using the readily available functionalized alkynes and UPy-thiol to affirm the simplicity and versatility of the methodology.

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