Journal
JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 53, Issue 2, Pages 345-355Publisher
WILEY
DOI: 10.1002/jhet.2415
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Funding
- European Union [FP7-KBBE-2009-3-245137]
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The 2-aminoimidazole (2-AI) ring is used widely as a building block in the design of new biologically active compounds, because of its good physico-chemical properties and potent activity in various test systems. Many marine alkaloids contain the 2-AI moiety. As a consequence, many synthetic routes have been developed in the total synthesis of natural compounds. The review covers all synthetic procedures for construction of 2-AI in particular and its analogs up to December 2014.
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