4.4 Article

DBU Acetate Mediated: One-pot Multi Component Syntheses of Dihydropyrano[3,2-c]quinolones

Journal

JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 53, Issue 6, Pages 1911-1916

Publisher

WILEY
DOI: 10.1002/jhet.2506

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Three-component reaction involving condensation of 1-methylquinoline-2,4(1H,3H)-dione(1), aromatic aldehydes 2(a-h) and malononitrile/cyanoaceticester 3(a,b) in{(1,8-diazabicyclo[5.4.0]-undec-7-en-8-ium acetate)}[DBU][Ac] as task-specific ionic liquid leading to the efficient synthesis of dihydropyrano[3,2-c] quinolones 4(a-p) is described. This approach is convenient, mild, and affords the products in high yields without the use of column chromatography.

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