4.6 Review

Recent Developments in the Synthesis of Five- and Six-Membered Heterocycles Using Molecular Iodine

Journal

CHEMISTRY-A EUROPEAN JOURNAL
Volume 18, Issue 18, Pages 5460-5489

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201100324

Keywords

catalysis; heterocycles; iodine; multicomponent reactions; synthetic methods

Funding

  1. DST
  2. CSIR, New Delhi

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Heterocyclic scaffolds represent the key structural subunits of many biologically active compounds. Over the last few years iodine-mediated reactions have been extensively studied due to their low cost and eco-friendliness. This Review covers advances in the field of iodine-mediated synthesis of heterocyclic compounds since 2006, especially with an emphasis on mechanisms of ring formation. In this article, syntheses of different heterocycles are classified based on the manipulation of functional groups.

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