Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 16, Issue 44, Pages 13243-13252Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201001520
Keywords
allenes cyclization; gold palladium platinum
Categories
Funding
- DGI-MICINN [CTQ2009-09318]
- Comunidad Autonoma de Madrid
- UCM-BSCH [GR58/08]
- EU [S2009/PPQ-1752]
Ask authors/readers for more resources
Versatile routes that lead to a variety of functionalized enantiopure tetrahydrofurans, dihydropyrans, and tetrahydrooxepines are based on chemo, regio, and stereocontrolled metal catalyzed oxycyclization reactions of beta,gamma and gamma,delta-allendiols, which were readily prepared from (R) 2,3-O-isopropylideneglyceraldehyde The application of Pd-II, Pt-II, Au-III, or La-III salts as the catalysts gives controlled access to differently sued oxacycles in enantiopure form Usually, chemoselective cyclization reactions occurred exclusively by attack of the secondary hydroxy group (except for the oxybromination of phenyl beta,gamma-allenic chols 3b and 3d) to an allenic carbon atom Regio- and stereocontrol issues are mainly influenced by the nature of the metal catalysts and substituents
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available