New Iridium Catalysts for the Efficient Alkylation of Anilines by Alcohols under Mild Conditions

The synthesis of eight new iridium complexes containing anionic PN ligands is described These complexes have been investigated as catalysts for amine alkylation reactions, resulting in a highly active catalyst for the selective monoalkylation of anilines with primary alcohols under mild reaction conditions Nearly quantitative conversion was observed at 70 degrees C with a catalyst loading as low as 0 05 mol % iridium