Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 16, Issue 7, Pages 2072-2078Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.200902999
Keywords
asymmetric synthesis; iodine; oxygen heterocycles; sorangicin A
Categories
Funding
- Council of Scientific & Industrial Research (CSIR), New Delhi, India
Ask authors/readers for more resources
A novel iodine-catalyzed highly diastereoselective synthesis of trans-2,6-disubstituted-3,4-dihydropyrans have been achieved from delta-hydroxy alpha,beta-unsaturated aldehydes by treating with allyltrimethyl silane in THF at room temperature with good to excellent yields. This methodology has been successfully implemented for a concise asymmetric synthesis of C28-C37 dioxabicyclo[3.2.1]octane ring system of (+)-sorangicin A in 8 steps with 21% overall yield
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available