4.6 Article

Structural Requirements for the Antiproliferative Activity of Pre-mRNA Splicing Inhibitor FR901464

Related references

Note: Only part of the references are listed.
Article Chemistry, Medicinal

Synthetic mRNA Splicing Modulator Compounds with in Vivo Antitumor Activity

Chandraiah Lagisetti et al.

JOURNAL OF MEDICINAL CHEMISTRY (2009)

Article Chemistry, Organic

Hemi-Phorboxazole A: Structure Confirmation, Analogue Design and Biological Evaluation

Amos B. Smith et al.

ORGANIC LETTERS (2009)

Article Multidisciplinary Sciences

Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibition

Jerome Clerc et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biochemistry & Molecular Biology

Disparate proteome reactivity profiles of carbon electrophiles

Eranthie Weerapana et al.

NATURE CHEMICAL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

How rapidly do Epoxides nonspecifically form covalent bonds with Thiols in water?

Brian I. Albert et al.

CHEMBIOCHEM (2007)

Article Biochemistry & Molecular Biology

Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA

Daisuke Kaida et al.

NATURE CHEMICAL BIOLOGY (2007)

Article Chemistry, Multidisciplinary

Total syntheses, fragmentation studies, and antitumor/antiproliferative activities of FR901464 and its low picomolar analogue

Brian J. Albert et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

Article Chemistry, Organic

Total syntheses of FR901464

Kazunori Koide et al.

JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN (2007)

Article Biotechnology & Applied Microbiology

Opinion - Why is cancer drug discovery so difficult?

Alexander Kamb et al.

NATURE REVIEWS DRUG DISCOVERY (2007)

Article Chemistry, Multidisciplinary

Total synthesis of FR901464, an antitumor agent that regulates the transcription of oncogenes and tumor suppressor genes

BJ Albert et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

Article Chemistry, Organic

Design and synthesis of a potent phorboxazole C(11-15) acetal analogue

AB Smith et al.

ORGANIC LETTERS (2006)

Article Chemistry, Organic

Total synthesis of FR901464: second generation

H Motoyoshi et al.

TETRAHEDRON (2006)

Article Oncology

Proteasome inhibition as a novel therapeutic target in human cancer

SV Rajkumar et al.

JOURNAL OF CLINICAL ONCOLOGY (2005)

Article Chemistry, Multidisciplinary

Nitro-substituted Hoveyda-Grubbs ruthenium carbenes: Enhancement of catalyst activity through electronic activation

A Michrowska et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)

Article Chemistry, Organic

Synthesis of a C4-epi-C1-C6 fragment of FR901464 using a novel bromolactolization

BJ Albert et al.

ORGANIC LETTERS (2004)

Article Biochemistry & Molecular Biology

Structure-activity relationship for FR901464: A versatile method tor the conversion and preparation of biologically active biotinylated probes

H Motoyoshi et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2004)

Article Multidisciplinary Sciences

Comprehensive proteomic analysis of the human spliceosome

ZL Zhou et al.

NATURE (2002)

Article Chemistry, Organic

An unexpected equilibrium process associated with a standard approach to ynone synthesis

MM Jackson et al.

JOURNAL OF ORGANIC CHEMISTRY (2002)

Review Biotechnology & Applied Microbiology

Glivec (ST1571, Imatinib), a rationally developed, targeted anticancer drug

R Capdeville et al.

NATURE REVIEWS DRUG DISCOVERY (2002)

Article Chemistry, Organic

A synthesis of FR901464

M Horigome et al.

TETRAHEDRON LETTERS (2001)

Article Chemistry, Multidisciplinary

FR901464: Total synthesis, proof of structure, and evaluation of synthetic analogues

CF Thompson et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)

Article Biochemistry & Molecular Biology

A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site

CL Will et al.

EMBO JOURNAL (2001)

Article Chemistry, Multidisciplinary

Total synthesis of FR901464. Convergent assembly of chiral components prepared by asymmetric catalysis

CF Thompson et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)