A Ratiometric Fluorescent Probe for Hypochlorite Based on a Deoximation Reaction

In this work, we have successfully provided a novel strategy for the rational design and synthesis of a ratiometric fluorescent probe for hypochlorite, The strategy is based on the deoximation reaction, which has not yet been used in the fluorescent hypochlorite probe design. Interestingly, the probe showed a ratiometric fluorescent response to hypochlorite with the emission intensities ratio increasing from 0.28 to 2.74. Furthermore, the probe displayed high selectivity for hypochlorite over other species due to the distinct deoximation conditions. The probe developed herein represents the first ratiometric fluorescent probe for hypochlorite.