4.6 Article

Ligand-free Sonogashira coupling reactions with heterogeneous Pd/C as the catalyst

Journal

CHEMISTRY-A EUROPEAN JOURNAL
Volume 14, Issue 23, Pages 6994-6999

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.200800387

Keywords

alkynes; C-C coupling; environmental chemistry; heterogeneous catalysis; palladium

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A variety of aryl iodides were coupled with aromatic and aliphatic terminal alkynes to give the corresponding 1,2-distributed aromatic alkynes in good yields by using only 0.4 mol% of the heterogeneous 10% Pd/C as the catalyst without a ligand, copper salt, or amine in an aqueous medium.

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