Journal
CHEMISTRY OF NATURAL COMPOUNDS
Volume 47, Issue 6, Pages 893-895Publisher
SPRINGER
DOI: 10.1007/s10600-012-0097-4
Keywords
Alternaria sp.; dibenzofuran; Staphyloccocus aureus
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Funding
- Fundamental Research Funds for the Central Universities [2010ZY18, 2011YXL025]
- Research Fund for the Doctoral Program of Higher Education of China [200804911002]
- China University of Geosciences [51900961135]
- National Natural Science Foundation of China [30901849]
- Science and Technology Planning Project of Zhejiang Province, China [2009C33004]
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Porric acid D (1), a new dibenzofuran derivative, was isolated from the methanol extract of a marine-derived fungus, Alternaria sp., isolated from the Bohai Sea, together with a known compound, altenusin. Their structures were elucidated by spectroscopic analysis, including high-resolution mass spectroscopy, and 1 and 2-dimensional NMR techniques. Compounds 1 and 2 showed inhibitory activity against Staphyloccocus aureus with MIC 100 and 25 mu g/mL, respectively.
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