Journal
CHEMISTRY OF NATURAL COMPOUNDS
Volume 47, Issue 6, Pages 870-875Publisher
SPRINGER
DOI: 10.1007/s10600-012-0091-x
Keywords
brown algae; Padina; polysaccharides; laminaran; fucoidan; alginic acid; biological activity
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Funding
- RFBR [09-04-00761-a]
- Molecular Cellular Biology Program
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The variation of the polysaccharide composition of the brown alga Padina pavonica from the Mediterranean Sea was studied as a function of the collection season (April-July). It was shown that the principal polysaccharide (8.0-13.3% of dry alga weight) was alginic acid. Its content did not undergo significant changes from April to July. The content of water-soluble polysaccharides (laminarans and fucoidans) was low (<0.3% of dry alga weight). Water-soluble polysaccharides of the studied alga were practically pure fucoidan. The amount of laminarans was insignificant (<0.01% of dry alga weight). The content of fucoidans increased in alga samples from May through July. It was shown that P. pavonica is a promising source of alginic acids, which have a high capacity for gelation, and fucoidans, which exhibit antitumor action against RPMI-7951 human melanoma cells.
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