FUROSTANE-TYPE STEROIDAL SAPONIN FROM Digitalis ciliata

A new furostane-type steroidal glycoside and derivative of tigogenin (1) was isolated from aqueous wastes from production of the cardiac drug acetyldigitoxin from leaves of Digitalis ciliata Trautv. (Scrophulariaceae) and characterized. The structure of the glycoside was established using physical constants, chemical transformations, and spectral data as 3-O-beta-D-glucopyranosyl-(1 -> 3) [beta-D-fucopyranosyl-(1 -> 2)-beta-D-glucopyranosyl-(1 -> 4)-beta-D-galactopyranosyl-(25R)-5 alpha-furostan-3 beta,22 alpha,26-triol-26-O-beta-D-glucopyranoside.