Journal
CHEMISTRY OF HETEROCYCLIC COMPOUNDS
Volume 50, Issue 2, Pages 139-144Publisher
SPRINGER
DOI: 10.1007/s10593-014-1456-9
Keywords
7-deazapurines; drug discovery; heterocycle; multicomponent reactions; privileged scaffold
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Funding
- Texas State University
- Welch Foundation [AI-0045]
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Multicomponent reactions are emerging as a powerful tool in the synthesis of heterocyclic privileged medicinal scaffolds. This highlight describes a recently developed approach to the construction of the medicinally important pyrrolo[2,3-d]pyrimidine scaffold using a one-pot synthesis from commercially available starting materials via novel multicomponent reactions.
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