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CYCLOTHIOMETHYLATION OF PRIMARY AMINES WITH FORMALDEHYDE AND HYDROGEN SULFIDE TO NITROGEN- AND SULFUR-CONTAINING HETEROCYCLES (REVIEW)

Journal

CHEMISTRY OF HETEROCYCLIC COMPOUNDS
Volume 45, Issue 10, Pages 1155-1176

Publisher

SPRINGER
DOI: 10.1007/s10593-010-0403-7

Keywords

1,3,5-dithiazinanes; 1,5-dithia-3,7-diazacyclooctane; 1,3,5-thiadiazinanes; 1,3-thiazetidines; N,S-containing heterocycles; cyclocondensation

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Published data and the authors' own experimental results on the synthesis of nitrogen-and sulfur-containing heterocycles based on the cyclothiomethylation of amines with formaldehyde and H2S are reviewed. Features of the three-component condensation are discussed in relation to the nature and structure of the initial amines and also the reaction conditions.

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