4.3 Article

Phosphine-catalyzed [3+2] and [3+3] Annulations of Azomethine Imines with Ethyl 2-Butynoate

Journal

CHEMISTRY LETTERS
Volume 41, Issue 3, Pages 218-220

Publisher

CHEMICAL SOC JAPAN
DOI: 10.1246/cl.2012.218

Keywords

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Funding

  1. National Natural Science Foundation of China [21172253]
  2. China Agricultural University [2011JS029, 2011JS031]
  3. National Scientific and Technology Supporting Program of China [2011BAE06B05-5]
  4. Key Technologies R&D Program of China [2012BAK25B03]
  5. Nutrichem Co.

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The phosphine-catalyzed [3 + 2] and [3 + 3] annulation reactions of azomethine imines and ethyl 2-butynoate were developed, providing 1,2-dinitrogen-containing heterocycles tetrahydropyrazolopyrazolones and tetrahydropyrazolopyridazinones in moderate to good yields.

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