Journal
CHEMISTRY LETTERS
Volume 41, Issue 1, Pages 47-49Publisher
CHEMICAL SOC JAPAN
DOI: 10.1246/cl.2012.47
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Funding
- Grants-in-Aid for Scientific Research [22220001, 23350079, 24655149] Funding Source: KAKEN
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Photoresponsibility of oligonucleotides containing 5-vinyl-2'-deoxyuridine derivatives having an aromatic group and its selectivity for 5-methylcytosine (C-m) were evaluated. Their high extinction coefficient and hydrophobicity caused C-m selective photoligation with a 10- to 20-fold higher reaction rate than 5-cyanovinyl-2'-deoxyuridine, previously reported.
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