4.3 Article

Regioselective Hydrocarbamoylation of 1-Alkenes

Journal

CHEMISTRY LETTERS
Volume 41, Issue 3, Pages 298-300

Publisher

CHEMICAL SOC JAPAN
DOI: 10.1246/cl.2012.298

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Funding

  1. Grants-in-Aid for Scientific Research [21225005, 22105003] Funding Source: KAKEN

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Nickel/Lewis acid cooperative catalysis derived from [Ni(cod)(2)], AlEt3, and N-heterocyclic carbene (NHC) effects highly regioselective hydrocarbamoylation of 1-alkenes. Variously substituted formamides and 1-alkenes can be employed to give a range of linear alkanamides regioselectively.

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