4.3 Article

Pd(II)-catalyzed Cross-coupling of C(sp2)-H Bonds and Alkyl-, Aryl-, and Vinyl-Boron Reagents via Pd(II)/Pd(0) Catalysis

Journal

CHEMISTRY LETTERS
Volume 40, Issue 9, Pages 1004-1006

Publisher

CHEMICAL SOC JAPAN
DOI: 10.1246/cl.2011.1004

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Funding

  1. Scripps Research Institute
  2. National Institutes of Health (NIGMS) [1 R01 GM084019-02]
  3. Bristol Myers Squibb
  4. Agency for Science, Technology and Research (A*STAR) Singapore

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Pd(II)-catalyzed cross-coupling of ortho-C-H bonds in benzoic acid and phenylacetic acid amides with alkyl-, aryl-, and vinyl-boron reagents have been achieved via Pd(II)/Pd(0) catalysis, demonstrating the unprecedented versatility of C-H activation reactions.

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