Journal
CHEMISTRY LETTERS
Volume 39, Issue 12, Pages 1291-1293Publisher
CHEMICAL SOC JAPAN
DOI: 10.1246/cl.2010.1291
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Funding
- Ministry of Education, Culture, Sports, Science and Technology of Japan [20107007, 20360377, 20560732, 21560813]
- Grants-in-Aid for Scientific Research [21560813, 20560732] Funding Source: KAKEN
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Clustering of lipid rafts in plasma membranes by hybrid liposomes (HL-23) composed of L-alpha-dimyristoylphosphatidylcholine (DMPC) and polyoxyethylene(23) dodecyl ether (C-12(EO)(23)) for human leukemia HL-60 cells was observed for the first time It was suggested that the induction of apoptosis by HL-23 could be related to an Increase of membrane fluidity and the formation of lipid rafts in the plasma membranes of HL-60 cells
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