Journal
CHEMISTRY LETTERS
Volume 39, Issue 10, Pages 1030-1032Publisher
CHEMICAL SOC JAPAN
DOI: 10.1246/cl.2010.1030
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Funding
- NMMBA [99200321, 99200322]
- APORC
- NSYSU [96C031702]
- National Science Council, Taiwan [NSC 98-2323-B-291-001, 98-2320-B-291-001-MY3]
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Chemical investigation on a cultured octocoral identified as Briareum sp has led to the isolation of a new 12-hydroperoxybriarane, briarenolide D (1) and a known briarane, 2 beta-acetoxy-2-(debutyryloxy)stecholide E (2) The structure of briarane 1 was established by spectroscopic methods and the structure of 2 was further confirmed by X-ray data analysis for the first time Cytotoxicity of hydroperoxybriarane 1 toward various tumor cell lines is also described
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