Generation and Reactions of α-Silyloxiranyllithium in a Microreactor

alpha-Triphenylsilyloxiranyllithium was effectively generated by the reaction of epoxyethyltriphenylsilane with n-BuLi in a microflow reactor at VC, though it is well known that an over reaction cannot be avoided even at lower temperatures in a conventional macrobatch reactor. Subsequent reactions with various electrophiles in the microflow reactor gave the corresponding alpha-substituted epoxysilanes.