4.3 Article

Pulsed Ultrasound Effect on DNA Polymerase Reaction Monitored on a QCM

Journal

CHEMISTRY LETTERS
Volume 38, Issue 6, Pages 538-539

Publisher

CHEMICAL SOC JAPAN
DOI: 10.1246/cl.2009.538

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DNA polymerase reaction under pulsed ultrasound irradiation was investigated on a DNA-immobilized quartz-crystal microbalance QCM), and the 240-kHz ultrasound irradiation pulsed at 20s(-1) increased the polymerization reactivity owing to the increase of the stability of the DNA/polymerase/monomer complex, although the continuous irradiation decreases the stability.

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