Journal
CHEMISTRY AND PHYSICS OF LIPIDS
Volume 154, Issue 1, Pages 64-67Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.chemphyslip.2008.03.007
Keywords
lipids; spontaneous curvature; DOPG
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Phosphatidylglycerol (PG) is an anionic lipid commonly found in large proportions in the cell membranes of bacteria and plants and, to a lesser extent, in animal cells. PG plays an important role in the regulation and determination of the elastic properties of the membrane. Using small angle X-ray scattering experiments, we obtain that the monolayer spontaneous curvature of dioleoylphosphatidylglycerol (DOPG) is -1/150 +/- 0.021 nm(-1) when measured in 150mM NaCl. When the experiments are carried out in 150 mM NaCl and 20 mM MgCl2, the value obtained for the monolayer spontaneous curvature is -1/8.7 +/- 0.037 nm(-1). These values are of importance in modelling the effects of curvature elastic stress in membrane lipid homeostasis in the bacterium Acholeplasma laidlawii [Alley, S.H., Barahona, M., Ces, O., Templer, R.H., in press. Biophysical regulation of lipid biosynthesis in the plasma membrane. Biophys. J.] and indicate that divalent cations can play a significant role in altering curvature elastic stress. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
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