Journal
JOURNAL OF HEMATOLOGY & ONCOLOGY
Volume 8, Issue -, Pages -Publisher
BIOMED CENTRAL LTD
DOI: 10.1186/s13045-015-0126-4
Keywords
Zebrafish; Leukemia; Myeloproliferative disorder; Myelodysplastic syndrome
Categories
Funding
- Deakin University
- Centre for Molecular and Medical Research
- Alfred Deakin Postdoctoral Research Fellow scheme
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Zebrafish is an established model for the study of vertebrate development, and is especially amenable for investigating hematopoiesis, where there is strong conservation of key lineages, genes, and developmental processes with humans. Over recent years, zebrafish has been increasingly utilized as a model for a range of human hematopoietic diseases, including malignancies. This review provides an overview of zebrafish hematopoiesis and describes its application as a model of leukemia and other hematopoietic disorders.
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