Journal
JOURNAL OF HEMATOLOGY & ONCOLOGY
Volume 8, Issue -, Pages -Publisher
BMC
DOI: 10.1186/s13045-015-0185-6
Keywords
Checkpoint inhibitors; Gastrointestinal cancers; Immunotherapy; Pembrolizumab; Nivolumab; PD-1; PD-L1; Biomarkers
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Gastrointestinal cancers are a group of highly aggressive malignancies, and novel therapeutic strategies with higher clinical efficacy are being actively sought. 'Immunotherapy' is now emerging as one such promising strategy for the treatment of these tumors. This article briefly reviews the recent advances that utilize targeting of immune checkpoint pathways, in the management of gastrointestinal malignancies.
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