Journal
CHEMISTRY & BIOLOGY
Volume 18, Issue 3, Pages 277-278Publisher
CELL PRESS
DOI: 10.1016/j.chembiol.2011.03.002
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Janus kinases are important signaling proteins implicated in cytokine signaling. In particular, Janus kinase 3 (JAK3) has gained attention as a target for inhibition of the immune system, due to its importance for T and B cell development and function. In this issue however, Haan et al. (2011) show that inhibition of JAK3 activity may not be sufficient for this purpose.
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