Journal
CHEMISTRY & BIOLOGY
Volume 15, Issue 11, Pages 1141-1147Publisher
CELL PRESS
DOI: 10.1016/j.chembiol.2008.10.010
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Communication through quorum sensing (OS) enables bacterial populations to coordinate their behavior. Recent work on N-acylhomoserine lactone-mediated QS has revealed that some soil bacteria exploit host-derived substrates to generate an alternative N-substituted homoserine lactone. New light has also been shed on the mechanism by which N-(3-oxo-dodecanoyl)-L-homoserine lactone modulates host inflammatory signaling pathways to promote bacterial survival.
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