4.5 Article

Antifungal Bromophenols from Marine Red Alga Symphyocladia latiuscula

Journal

CHEMISTRY & BIODIVERSITY
Volume 11, Issue 5, Pages 807-811

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.201300239

Keywords

Symphyocladia latiuscula; Polyphenols; brominated; Antifungal activity; Candida albicans

Funding

  1. Fundamental Research Funds for the Central Universities [2652012121, 2652010098]

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Three new highly brominated polyphenols, 1-3, together with one known bromophenol, 4, were isolated from the EtOH extract of a marine red alga Symphyocladia latiuscula collected from the coast of Qingdao, P.R. China. Their structures were identified by extensive spectroscopic experiments (NMR and MS) and comparison with literature data. Compounds 3 and 4 showed activities against the Candida albicans with the MIC values of 25 and 12.5g/ml, respectively.

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