Journal
CHEMISTRY & BIODIVERSITY
Volume 11, Issue 5, Pages 812-818Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.201300265
Keywords
Anthogorgia caerulea; Avermectins B-1c and B-1e; Antifouling activity
Funding
- National Natural Science Foundation of China [31100260, 81260480]
- Knowledge Innovation Program of Chinese Academy of Sciences [KSCX2-EW-J-28]
- Program of Guangzhou City [12C14061559]
- Natural Science Foundation of Guangxi [2010GXNSFE013001, 2011GXNSFE018002, 2011GXNSFB018035, 2011GXNSFA018108, 2012GXNSFAA053160, 2012GXNSFEA053001, 2012GXNSFBA053068]
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Two new avermectin derivatives, avermectins B-1c and B-1e (1 and 2, resp.), as well as two known compounds, avermectin B-2a (3) and ivermectin A(1a) (4), were isolated from a Beibu Gulf gorgonian coral, Anthogorgia caerulea. The structures of the new compounds were established by detailed spectroscopic analysis and by comparison with spectral data of related known compounds. Compounds 1-4 showed moderate antifouling activities against the larval settlement of Balanus amphitrite.
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