Journal
CHEMISTRY & BIODIVERSITY
Volume 9, Issue 2, Pages 394-402Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.201100072
Keywords
Artocarpus hypargyreus; Flavones; Stilbenes; Hypargyflavones A?-?C; Hypargystilbene A; Pancreatic lipase; Inhibitors
Funding
- Science and Technology Commission of Shanghai Municipality [09dZ1976100]
- Program for New Century Excellent Talents in University [NCET-09-0313]
- National Drug Innovative Program [2009ZX09301-011]
- State Key Laboratory of Drug Research (Shanghai Institute of Materia Medica, Chinese Academy of Sciences)
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Three new isoprenylated flavones, hypargyflavones AC (13, resp.), and one novel stilbene derivative, hypargystilbene A (4), together with seven known compounds, 511, were isolated from the stems of Artocarpus hypargyreus Hance. The structures were elucidated by spectroscopic methods. Hypargyflavone A (1), cudraflavone C (8), brosimone I (10), and norartocarpin (11) showed inhibitory effects on pancreatic lipase.
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