Journal
CHEMISTRY & BIODIVERSITY
Volume 8, Issue 11, Pages 2015-2024Publisher
WILEY-BLACKWELL
DOI: 10.1002/cbdv.201000367
Keywords
Flavanones; Cryptoflavanones A?-?D; Cryptocarya chinensis; Antituberculosis activity
Funding
- National Science Council of the Republic of China [NSC 96-2628-B-037-003-MY3]
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Four new flavanones, cryptoflavanones AD (14, resp.), together with eight known compounds, were isolated from the leaves of Cryptocarya chinensis. The structures of these new compounds were determined by spectral analyses. Among the isolated compounds, pinocembrin (5) and cryptocaryone (6) exhibited antituberculosis activity against Mycobacterium tuberculosis H37Rv strain in vitro with MIC values of 3.5 and 25.0 mu g/ml, respectively.
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