Journal
CHEMISTRY & BIODIVERSITY
Volume 6, Issue 5, Pages 746-753Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.200800054
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Three novel fernane-type triterpenoids, lobarialides A-C (1-3, resp.), together with two known ones were isolated by antifungal bioassay-guided fractionation of the lichen Lobaria kurokawae. Their structures including configurations were established on the basis of extensive spectroscopic analyses, and that of 1 was confirmed by a single-crystal X-ray diffraction analysis. Antifungal tests of the five triterpenoids showed that the activity increased with the increment of the number of COO groups.
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