Journal
CHEMISTRY & BIODIVERSITY
Volume 6, Issue 3, Pages 411-420Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.200800135
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Funding
- Academic browier Project, and a Grant-in Aid for Scientific Research from MEXT , Ministry of Education, Culture, Sports. Science (and Technology of Japan)
- High-Tech Research Center Project (2007-2011)
- Scientific Research from MEXT
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Six new acylated flavonol bisdesmosides, sinocrassosides A(3), A(4), A(5), A(6), A(7) and B-3 (1-6, resp.), were isolated from the MeOH extract of the whole plant of Sinocrassida indica. The Structures Of 1-6 were elucidated on the basis of chemical and physicochemical evidence. Among them, 2 and 6 which have an acyl group in the 3'''-position were found to show strong inhibitory effects on aminopeptidase N activity, which were stronger than that of curcumin.
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