Journal
CHEMICAL SOCIETY REVIEWS
Volume 47, Issue 21, Pages 7996-8017Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cs00389k
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Funding
- University of Illinois
- NSF
- Bristol-Myers Squibb
- Robert C. and Carolyn J. Springborn Graduate fellowship
- NIGM
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Dearomatization reactions provide a synthetic connection between readily available, simple aromatic starting materials and more saturated intermediates of greater molecular complexity and synthetic utility. The last decade has witnessed a steady increase in the development of dearomative methods, providing new synthetic approaches to high-value building blocks and natural products. This review highlights advances both in the area of dearomatization methodologies for the most chemically inert arenes and in synthetic applications of such strategies.
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