Journal
CHEMICAL SOCIETY REVIEWS
Volume 43, Issue 10, Pages 3575-3594Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cs60384a
Keywords
-
Categories
Ask authors/readers for more resources
Peptidomimetics represent an important field in chemistry, pharmacology and material science as they circumvent the limitations of traditional peptides used in therapy. Self-structural organizations such as turns, helices, sheets and loops can be accessed by chemical modifications of amino acids or peptides. In-depth structural and conformational analysis and structure-activity relationships (SAR) offer a way to establish peptidomimetic libraries. Herein, we review recent developments in peptidomimetics that are formed via heteroatom replacement within the native amino acid backbone. Each sub-section describes structural features, utility and preparative methods.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available